Myeloid IκBα Deficiency Promotes Atherogenesis by Enhancing Leukocyte Recruitment to the Plaques

Activation of the transcription factor NF-κB appears to be involved in different stages of atherogenesis. In this paper we investigate the role of NF-κB inhibitor IκBα in atherosclerosis. Myeloid-specific deletion of IκBα results in larger and more advanced lesions in LDL-R-deficient mice without af...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Goossens, Pieter, Vergouwe, Monique N., Gijbels, Marion J. J., Curfs, Danielle M. J., van Woezik, Johannes H. G., Hoeksema, Marten A., Xanthoulea, Sofia, Leenen, Pieter J. M., Rupec, Rudolf A., Hofker, Marten H., de Winther, Menno P. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141029/
https://ncbi.nlm.nih.gov/pubmed/21814576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022327
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares