Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor–deficient mice
Atherosclerosis is now generally accepted as a chronic inflammatory condition. The transcription factor NF-κB is a key regulator of inflammation, immune responses, cell survival, and cell proliferation. To investigate the role of NF-κB activation in macrophages during atherogenesis, we used LDL rece...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC213488/ https://ncbi.nlm.nih.gov/pubmed/14561702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318580 |
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