Use of MicroRNA Let-7 to Control the Replication Specificity of Oncolytic Adenovirus in Hepatocellular Carcinoma Cells

Highly selective therapy for hepatocellular carcinoma (HCC) remains an unmet medical need. In present study, we found that the tumor suppressor microRNA, let-7 was significantly downregulated in a proportion of primary HCC tissues (12 of 33, 36.4%) and HCC cell lines. In line with this finding, we h...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Jin, Huajun, Lv, Saiqun, Yang, Jiahe, Wang, Xiaoning, Hu, Huanzhang, Su, Changqing, Zhou, Chengliang, Li, Jiang, Huang, Yao, Li, Linfang, Liu, Xinyuan, Wu, Mengchao, Qian, Qijun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140979/
https://ncbi.nlm.nih.gov/pubmed/21814544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021307
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker