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HSF1 overexpression enhances oncolytic effect of replicative adenovirus

BACKGROUND: E1B55kD deleted oncolytic adenovirus was designed to achieve cancer-specific cytotoxicity, but showed limitations in clinical study. To find a method to increase its efficacy, we investigated the correlation between oncolytic effect of such oncolytic adenovirus Adel55 and intracellular h...

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Detalhes bibliográficos
Main Authors: Wang, Cheng, Dai, Zhehao, Fan, Rong, Deng, Youwen, Lv, Guohua, Lu, Guangxiu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877000/
https://ncbi.nlm.nih.gov/pubmed/20459615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-44
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