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Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations

Cerebral cavernous malformations (CCM) are irregularly shaped and enlarged capillaries in the brain that are prone to hemorrhage, resulting in headaches, seizures, strokes and even death in patients. The disease affects up to 0.5% of the population and the inherited form has been linked to mutations...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cunningham, Kirk, Uchida, Yutaka, O'Donnell, Erin, Claudio, Estefania, Li, Wenling, Soneji, Kosha, Wang, Hongshan, Mukouyama, Yoh-suke, Siebenlist, Ulrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140822/
https://ncbi.nlm.nih.gov/pubmed/21596842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr225
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