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Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations

Cerebral cavernous malformations (CCM) are irregularly shaped and enlarged capillaries in the brain that are prone to hemorrhage, resulting in headaches, seizures, strokes and even death in patients. The disease affects up to 0.5% of the population and the inherited form has been linked to mutations...

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書誌詳細
主要な著者: Cunningham, Kirk, Uchida, Yutaka, O'Donnell, Erin, Claudio, Estefania, Li, Wenling, Soneji, Kosha, Wang, Hongshan, Mukouyama, Yoh-suke, Siebenlist, Ulrich
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140822/
https://ncbi.nlm.nih.gov/pubmed/21596842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr225
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