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Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations

Cerebral cavernous malformations (CCM) are irregularly shaped and enlarged capillaries in the brain that are prone to hemorrhage, resulting in headaches, seizures, strokes and even death in patients. The disease affects up to 0.5% of the population and the inherited form has been linked to mutations...

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Detalhes bibliográficos
Main Authors: Cunningham, Kirk, Uchida, Yutaka, O'Donnell, Erin, Claudio, Estefania, Li, Wenling, Soneji, Kosha, Wang, Hongshan, Mukouyama, Yoh-suke, Siebenlist, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140822/
https://ncbi.nlm.nih.gov/pubmed/21596842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr225
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