Celastrol Inhibits Tat-mediated Human Immunodeficiency Virus (HIV) Transcription and Replication

Current drugs used for anti-retroviral therapy against HIV have a narrow spectrum of activity, and more often have associated toxicities and severe side effects in addition to developing resistance. Thus, there is a need to develop new therapeutic strategies against HIV/AIDS to complement the alread...

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Bibliographic Details
Main Authors: Narayan, Vivek, Kodihalli, Ravindra C., Chiaro, Chris, Cary, Daniele, Aggarwal, Bharat B., Henderson, Andrew J., Prabhu, K. Sandeep
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140654/
https://ncbi.nlm.nih.gov/pubmed/21763500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.013
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