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IFNα CONFERS RESISTANCE OF SLE NEPHRITIS TO THERAPY IN NZB/WF1 MICE
The critical role of IFNα in the pathogenesis of human systemic lupus erythematosus (SLE) has been highlighted in recent years. Exposure of young lupus-prone NZB/W F1 mice to IFNα in vivo leads to an accelerated lupus phenotype that is dependent on T cells and is associated with elevated serum level...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140572/ https://ncbi.nlm.nih.gov/pubmed/21705616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004142 |
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