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Telomere dysfunction promotes metastasis in a Terc null mouse model of head and neck cancer

Squamous cell carcinoma arises from highly proliferative basal layer epithelial cells which normally divide for a short time before detaching from the basement membrane and undergoing terminal differentiation. Basal layer cells in stratified epithelia express the reverse transcriptase known as telom...

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Detalhes bibliográficos
Main Authors: Bojovic, Bojana, Crowe, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140542/
https://ncbi.nlm.nih.gov/pubmed/21593138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0345
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