A novel orthotopic mouse model of head and neck cancer and lymph node metastasis

Prognosis of head and neck squamous cell carcinoma (HNSCC) is largely determined by the extent of lymph node (LN) metastasis at diagnosis, and this appears to be controlled by cancer cell genetics. To examine the role of these genes in LN metastasis, we created a human-in-mouse orthotopic model of H...

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Autori principali: Masood, R, Hochstim, C, Cervenka, B, Zu, S, Baniwal, S K, Patel, V, Kobielak, A, Sinha, U K
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816223/
https://ncbi.nlm.nih.gov/pubmed/24018643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2013.33
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