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A novel orthotopic mouse model of head and neck cancer and lymph node metastasis

Prognosis of head and neck squamous cell carcinoma (HNSCC) is largely determined by the extent of lymph node (LN) metastasis at diagnosis, and this appears to be controlled by cancer cell genetics. To examine the role of these genes in LN metastasis, we created a human-in-mouse orthotopic model of H...

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Autors principals: Masood, R, Hochstim, C, Cervenka, B, Zu, S, Baniwal, S K, Patel, V, Kobielak, A, Sinha, U K
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816223/
https://ncbi.nlm.nih.gov/pubmed/24018643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2013.33
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