Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells

The CD4(+)Foxp3(+) lineage of regulatory T (Treg) cells plays a key role in controlling immune and autoimmune responses. Treg cells originate primarily during T cell differentiation in the thymus, but conversion of mature T lymphocytes to Foxp3-positivity can be elicited by several means, including...

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Bibliographische Detailangaben
Hauptverfasser: Hill, Jonathan A., Hall, Jason A., Sun, Cheng-Ming, Cai, Qi, Ghyselinck, Norbert, Chambon, Pierre, Belkaid, Yasmine, Mathis, Diane, Benoist, Christophe
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140207/
https://ncbi.nlm.nih.gov/pubmed/19006694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.09.018
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