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p190RhoGAP links the β1 integrin/caveolin-1 mechano-signaling complex to RhoA and actin remodeling
OBJECTIVE: Hemodynamic shear stress influences endothelial cell phenotype. Integrins and RhoA are essential components in the process that allow endothelial cells to adapt to flow. However, the signaling mechanisms that relay from integrins to RhoA are not well defined. We hypothesized that the β1 i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140163/ https://ncbi.nlm.nih.gov/pubmed/21051664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.217794 |
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