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In Utero Exposure to Diethylstilbestrol (DES) or Bisphenol-A (BPA) Increases EZH2 Expression in the Mammary Gland: An Epigenetic Mechanism Linking Endocrine Disruptors to Breast Cancer

Diethylstilbestrol (DES) and bisphenol-A (BPA) are estrogen-like endocrine-disrupting chemicals that induce persistent epigenetic changes in the developing uterus. However, DES exposure in utero is also associated with an increased risk of breast cancer in adult women. Similarly, fetal exposure to B...

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Hlavní autoři: Doherty, Leo F., Bromer, Jason G., Zhou, Yuping, Aldad, Tamir S., Taylor, Hugh S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140020/
https://ncbi.nlm.nih.gov/pubmed/21761357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-010-0015-9
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