Antitumor Efficacy of a Thrombospondin 1 Mimetic CovX-Body

CVX-045 is produced by covalently attaching a thrombospondin 1 (TSP-1) mimetic comprising a peptidic sequence and a linker to the Fab binding site of a proprietary scaffold antibody. CVX-045 possesses the potency of the TSP-1-derived peptide, along with the advantageous pharmacokinetics of an antibo...

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Detalhes bibliográficos
Main Authors: Li, Lingna, Leedom, Tom A, Do, Janet, Huang, Hanhua, Lai, JingYu, Johnson, Kim, Osothprarop, Trina F, Rizzo, John D, Doppalapudi, Venkata R, Bradshaw, Curt W, Lappe, Rodney W, Woodnutt, Gary, Levin, Nancy J, Pirie-Shepherd, Steven R
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140013/
https://ncbi.nlm.nih.gov/pubmed/21804921
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