Melanopsin retinal ganglion cells are resistant to neurodegeneration in mitochondrial optic neuropathies

Mitochondrial optic neuropathies, that is, Leber hereditary optic neuropathy and dominant optic atrophy, selectively affect retinal ganglion cells, causing visual loss with relatively preserved pupillary light reflex. The mammalian eye contains a light detection system based on a subset of retinal g...

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Bibliografiske detaljer
Main Authors: La Morgia, Chiara, Ross-Cisneros, Fred N., Sadun, Alfredo A., Hannibal, Jens, Munarini, Alessandra, Mantovani, Vilma, Barboni, Piero, Cantalupo, Gaetano, Tozer, Kevin R., Sancisi, Elisa, Salomao, Solange R., Moraes, Milton N., Moraes-Filho, Milton N., Heegaard, Steffen, Milea, Dan, Kjer, Poul, Montagna, Pasquale, Carelli, Valerio
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139936/
https://ncbi.nlm.nih.gov/pubmed/20659957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awq155
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