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Melanopsin retinal ganglion cells are resistant to neurodegeneration in mitochondrial optic neuropathies

Mitochondrial optic neuropathies, that is, Leber hereditary optic neuropathy and dominant optic atrophy, selectively affect retinal ganglion cells, causing visual loss with relatively preserved pupillary light reflex. The mammalian eye contains a light detection system based on a subset of retinal g...

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Sonraí Bibleagrafaíochta
Main Authors: La Morgia, Chiara, Ross-Cisneros, Fred N., Sadun, Alfredo A., Hannibal, Jens, Munarini, Alessandra, Mantovani, Vilma, Barboni, Piero, Cantalupo, Gaetano, Tozer, Kevin R., Sancisi, Elisa, Salomao, Solange R., Moraes, Milton N., Moraes-Filho, Milton N., Heegaard, Steffen, Milea, Dan, Kjer, Poul, Montagna, Pasquale, Carelli, Valerio
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139936/
https://ncbi.nlm.nih.gov/pubmed/20659957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awq155
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