Melanopsin retinal ganglion cells are resistant to neurodegeneration in mitochondrial optic neuropathies

Mitochondrial optic neuropathies, that is, Leber hereditary optic neuropathy and dominant optic atrophy, selectively affect retinal ganglion cells, causing visual loss with relatively preserved pupillary light reflex. The mammalian eye contains a light detection system based on a subset of retinal g...

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Bibliographische Detailangaben
Hauptverfasser: La Morgia, Chiara, Ross-Cisneros, Fred N., Sadun, Alfredo A., Hannibal, Jens, Munarini, Alessandra, Mantovani, Vilma, Barboni, Piero, Cantalupo, Gaetano, Tozer, Kevin R., Sancisi, Elisa, Salomao, Solange R., Moraes, Milton N., Moraes-Filho, Milton N., Heegaard, Steffen, Milea, Dan, Kjer, Poul, Montagna, Pasquale, Carelli, Valerio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139936/
https://ncbi.nlm.nih.gov/pubmed/20659957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awq155
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