Melanopsin retinal ganglion cell loss in Alzheimer disease

OBJECTIVE: Melanopsin retinal ganglion cells (mRGCs) are photoreceptors driving circadian photoentrainment, and circadian dysfunction characterizes Alzheimer disease (AD). We investigated mRGCs in AD, hypothesizing that they contribute to circadian dysfunction. METHODS: We assessed retinal nerve fib...

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Détails bibliographiques
Publié dans:Ann Neurol
Auteurs principaux: La Morgia, Chiara, Ross‐Cisneros, Fred N., Koronyo, Yosef, Hannibal, Jens, Gallassi, Roberto, Cantalupo, Gaetano, Sambati, Luisa, Pan, Billy X., Tozer, Kevin R., Barboni, Piero, Provini, Federica, Avanzini, Pietro, Carbonelli, Michele, Pelosi, Annalisa, Chui, Helena, Liguori, Rocco, Baruzzi, Agostino, Koronyo‐Hamaoui, Maya, Sadun, Alfredo A., Carelli, Valerio
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737313/
https://ncbi.nlm.nih.gov/pubmed/26505992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24548
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