Melanopsin retinal ganglion cell loss in Alzheimer disease

OBJECTIVE: Melanopsin retinal ganglion cells (mRGCs) are photoreceptors driving circadian photoentrainment, and circadian dysfunction characterizes Alzheimer disease (AD). We investigated mRGCs in AD, hypothesizing that they contribute to circadian dysfunction. METHODS: We assessed retinal nerve fib...

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Publicat a:Ann Neurol
Autors principals: La Morgia, Chiara, Ross‐Cisneros, Fred N., Koronyo, Yosef, Hannibal, Jens, Gallassi, Roberto, Cantalupo, Gaetano, Sambati, Luisa, Pan, Billy X., Tozer, Kevin R., Barboni, Piero, Provini, Federica, Avanzini, Pietro, Carbonelli, Michele, Pelosi, Annalisa, Chui, Helena, Liguori, Rocco, Baruzzi, Agostino, Koronyo‐Hamaoui, Maya, Sadun, Alfredo A., Carelli, Valerio
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737313/
https://ncbi.nlm.nih.gov/pubmed/26505992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24548
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