Melanopsin retinal ganglion cell loss in Alzheimer disease

OBJECTIVE: Melanopsin retinal ganglion cells (mRGCs) are photoreceptors driving circadian photoentrainment, and circadian dysfunction characterizes Alzheimer disease (AD). We investigated mRGCs in AD, hypothesizing that they contribute to circadian dysfunction. METHODS: We assessed retinal nerve fib...

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Bibliographic Details
Published in:Ann Neurol
Main Authors: La Morgia, Chiara, Ross‐Cisneros, Fred N., Koronyo, Yosef, Hannibal, Jens, Gallassi, Roberto, Cantalupo, Gaetano, Sambati, Luisa, Pan, Billy X., Tozer, Kevin R., Barboni, Piero, Provini, Federica, Avanzini, Pietro, Carbonelli, Michele, Pelosi, Annalisa, Chui, Helena, Liguori, Rocco, Baruzzi, Agostino, Koronyo‐Hamaoui, Maya, Sadun, Alfredo A., Carelli, Valerio
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737313/
https://ncbi.nlm.nih.gov/pubmed/26505992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24548
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