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HYPOXIA-INDUCED OVEREXPRESSION OF BNIP3 IS NOT DEPENDENT ON HIF-1α IN MOUSE HEPATOCYTES

We sought to investigate the expression of the cell death protein BNIP3 in hypoxic hepatocytes, as well as the role that HIF-1α plays in the upregulation of BNIP3 in hypoxic primary mouse hepatocytes and in the livers of mice subjected to ischemia/reperfusion. Freshly isolated mouse hepatocytes were...

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Bibliografski detalji
Glavni autori: Namas, Rajaie A., Metukuri, Mallikarjuna R., Dhupar, Rajeev, Velosa, Claudia, Jefferson, Bahiyyah S., Myer, Evan, Constantine, Greg M., Billiar, Timothy R., Vodovotz, Yoram, Zamora, Ruben
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139730/
https://ncbi.nlm.nih.gov/pubmed/21558981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3182205e07
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