Activation of latent transforming growth factor-β1 by nitric oxide in macrophages: Role of soluble guanylate cyclase and MAP kinases

The inducible nitric oxide (NO) synthase and the cytokine transforming growth factor-β1 (TGF-β1), both central modulators of wound healing, interact reciprocally: TGF-β1 generally suppresses iNOS expression, while NO can induce and activate latent TGF-β1. We have shown that chemical NO activates rec...

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Détails bibliographiques
Auteurs principaux: Metukuri, Mallikarjuna Reddy, Namas, Rajaie, Gladstone, Chase, Clermont, Thierry, Jefferson, Bahiyya, Barclay, Derek, Hermus, Linda, Billiar, Timothy R., Zamora, Ruben, Vodovotz, Yoram
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654795/
https://ncbi.nlm.nih.gov/pubmed/19614923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1524-475X.2009.00509.x
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