Broad-Spectrum Inhibition of HIV-1 by a Monoclonal Antibody Directed against a gp120-Induced Epitope of CD4

To penetrate susceptible cells, HIV-1 sequentially interacts with two highly conserved cellular receptors, CD4 and a chemokine receptor like CCR5 or CXCR4. Monoclonal antibodies (MAbs) directed against such receptors are currently under clinical investigation as potential preventive or therapeutic a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Burastero, Samuele E., Frigerio, Barbara, Lopalco, Lucia, Sironi, Francesca, Breda, Daniela, Longhi, Renato, Scarlatti, Gabriella, Canevari, Silvana, Figini, Mariangela, Lusso, Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139607/
https://ncbi.nlm.nih.gov/pubmed/21818294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022081
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi