Broad-Spectrum Inhibition of HIV-1 by a Monoclonal Antibody Directed against a gp120-Induced Epitope of CD4

To penetrate susceptible cells, HIV-1 sequentially interacts with two highly conserved cellular receptors, CD4 and a chemokine receptor like CCR5 or CXCR4. Monoclonal antibodies (MAbs) directed against such receptors are currently under clinical investigation as potential preventive or therapeutic a...

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Main Authors: Burastero, Samuele E., Frigerio, Barbara, Lopalco, Lucia, Sironi, Francesca, Breda, Daniela, Longhi, Renato, Scarlatti, Gabriella, Canevari, Silvana, Figini, Mariangela, Lusso, Paolo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139607/
https://ncbi.nlm.nih.gov/pubmed/21818294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022081
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