Location-Specific Epigenetic Regulation of the Metallothionein 3 Gene in Esophageal Adenocarcinomas

BACKGROUND: Metallothionein 3 (MT3) maintains intracellular metal homeostasis and protects against reactive oxygen species (ROS)-induced DNA damage. In this study, we investigated the epigenetic alterations and gene expression of the MT3 gene in esophageal adenocarcinomas (EACs). METHODS AND RESULTS...

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Bibliographic Details
Main Authors: Peng, DunFa, Hu, Tian-Ling, Jiang, Aixiang, Washington, Mary Kay, Moskaluk, Christopher A., Schneider-Stock, Regine, El-Rifai, Wael
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139601/
https://ncbi.nlm.nih.gov/pubmed/21818286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022009
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