Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide

BACKGROUND: Hypertension is, amongst others, characterized by endothelial dysfunction and vascular remodeling. As sphingolipids have been implicated in both the regulation of vascular contractility and growth, we investigated whether sphingolipid biology is altered in hypertension and whether this i...

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Autori principali: Spijkers, Léon J. A., van den Akker, Rob F. P., Janssen, Ben J. A., Debets, Jacques J., De Mey, Jo G. R., Stroes, Erik S. G., van den Born, Bert-Jan H., Wijesinghe, Dayanjan S., Chalfant, Charles E., MacAleese, Luke, Eijkel, Gert B., Heeren, Ron M. A., Alewijnse, Astrid E., Peters, Stephan L. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139577/
https://ncbi.nlm.nih.gov/pubmed/21818267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021817
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