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The Role of AGG Interruptions in the Transcription of FMR1 Premutation Alleles

Fragile X associated disorders are caused by a premutation allele in the fragile X mental retardation 1 gene (FMR1) and are hypothesized to result from the toxic effect of elevated levels of expanded FMR1 transcripts. Increased levels of FMR1 mRNA have indeed been reported in premutation carriers; h...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yrigollen, Carolyn M., Tassone, Federica, Durbin-Johnson, Blythe, Tassone, Flora
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139575/
https://ncbi.nlm.nih.gov/pubmed/21818263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021728
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