Absence of Transverse Tubules Contributes to Non-Uniform Ca(2+) Wavefronts in Mouse and Human Embryonic Stem Cell–Derived Cardiomyocytes

Mouse (m) and human embryonic stem cell-derived cardiomyocytes (hESC-CMs) are known to exhibit immature Ca(2+) dynamics such as small whole-cell peak amplitude and slower kinetics relative to those of adult. In this study, we examined the maturity and efficiency of Ca(2+)-induced Ca(2+) release in m...

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Autores principales: Lieu, Deborah K., Liu, Jing, Siu, Chung-Wah, McNerney, Gregory P., Tse, Hung-Fat, Abu-Khalil, Amir, Huser, Thomas, Li, Ronald A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. publishers 2009
Materias:
Original Research Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139544/
https://ncbi.nlm.nih.gov/pubmed/19290776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2009.0052
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