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Novel therapeutic strategies for neurodegenerative disease

The activity of protein phosphatase 2A (PP2A) is compromised and believed to be the cause of the abnormal hyperphosphorylation of tau in Alzheimer’s disease (AD) brain. Activity of PP2A is regulated by two endogeneous inhibitor proteins, called as I(1)(PP2A) and I(2)(PP2A). Previously, we reported t...

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Detalhes bibliográficos
Main Authors: TANIMUKAI, Hitoshi, KUDO, Takashi, TANAKA, Toshihisa, GRUNDKE-IQBAL, Inge, IQBAL, Khalid, TAKEDA, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139458/
https://ncbi.nlm.nih.gov/pubmed/19604333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1479-8301.2009.00289.x
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