CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense non-coding RNA

Spinocerebellar ataxia type 7 (SCA7) is a neurodegenerative disorder caused by CAG / polyglutamine repeat expansions in the ataxin-7 gene. Ataxin-7 is a component of two different transcription co-activator complexes, and recent work indicates that disease protein normal function is altered in polyg...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sopher, Bryce L., Ladd, Paula D., Pineda, Victor V., Libby, Randell T., Sunkin, Susan M., Hurley, James B., Thienes, Cortlandt P., Gaasterland, Terry, Filippova, Galina N., La Spada, Albert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139428/
https://ncbi.nlm.nih.gov/pubmed/21689595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.05.027
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados