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Structural Stability and Heme Binding Potential of the Truncated Human Dual Oxidase 2 (DUOX2) Peroxidase Domain
The essential role of human dual oxidase 2 (hDUOX2) in thyroid hormone biosynthesis defines this member of the NOX/DUOX family, whose absence due to mutation has been directly related to disease, specifically hypothyroidism. Both human DUOX isoforms, hDUOX1 and hDUOX2, are expressed in thyroid tissu...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139011/ https://ncbi.nlm.nih.gov/pubmed/21704604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.05.021 |
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