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Structural Stability and Heme Binding Potential of the Truncated Human Dual Oxidase 2 (DUOX2) Peroxidase Domain

The essential role of human dual oxidase 2 (hDUOX2) in thyroid hormone biosynthesis defines this member of the NOX/DUOX family, whose absence due to mutation has been directly related to disease, specifically hypothyroidism. Both human DUOX isoforms, hDUOX1 and hDUOX2, are expressed in thyroid tissu...

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Main Authors: Meitzler, Jennifer L., Ortiz de Montellano, Paul R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139011/
https://ncbi.nlm.nih.gov/pubmed/21704604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.05.021
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