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Up-regulation of the DR5 Expression by Proteasome Inhibitor MG132 Augments TRAIL-Induced Apoptosis in Soft Tissue Sarcoma Cell Lines

PURPOSE: Current chemotherapeutics for treating locally advanced or metastatic soft tissue sarcomas (STS) are limited. Accordingly, the present in vitro study was conducted to evaluate the effects of treatment of STS cells with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) applied...

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Autors principals: Cheong, Hee-Jeong, Lee, Kyu Sang, Woo, In Sook, Won, Jong-Ho, Byun, Jae Ho
Format: Artigo
Idioma:Inglês
Publicat: Korean Cancer Association 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138916/
https://ncbi.nlm.nih.gov/pubmed/21811429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2011.43.2.124
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