Immunoreactivity for Ano1 Detects Depletion of Kit-positive Interstitial Cells of Cajal in Patients with Slow Transit Constipation

BACKGROUND AND AIMS: Depletion of interstitial cells of Cajal (ICC) is associated with several gastrointestinal motility disorders. Changes in ICC networks are usually detected by immunolabeling for the receptor tyrosine kinase Kit. Ano1 (DOG1 or TMEM16A) was recently described as a marker of ICC in...

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Autores principales: Kashyap, Purna, Gomez-Pinilla, Pedro Julian, Pozo, Maria J., Cima, Robert R., Dozois, Eric J., Larson, David W., Ordog, Tamas, Gibbons, Simon J., Farrugia, Gianrico
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138829/
https://ncbi.nlm.nih.gov/pubmed/21585622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2011.01729.x
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