Immunoreactivity for Ano1 Detects Depletion of Kit-positive Interstitial Cells of Cajal in Patients with Slow Transit Constipation

BACKGROUND AND AIMS: Depletion of interstitial cells of Cajal (ICC) is associated with several gastrointestinal motility disorders. Changes in ICC networks are usually detected by immunolabeling for the receptor tyrosine kinase Kit. Ano1 (DOG1 or TMEM16A) was recently described as a marker of ICC in...

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Autori principali: Kashyap, Purna, Gomez-Pinilla, Pedro Julian, Pozo, Maria J., Cima, Robert R., Dozois, Eric J., Larson, David W., Ordog, Tamas, Gibbons, Simon J., Farrugia, Gianrico
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138829/
https://ncbi.nlm.nih.gov/pubmed/21585622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2011.01729.x
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