Metabolomic Profiling Reveals a Role for Androgen in Activating Amino Acid Metabolism and Methylation in Prostate Cancer Cells

Prostate cancer is the second leading cause of cancer related death in American men. Development and progression of clinically localized prostate cancer is highly dependent on androgen signaling. Metastatic tumors are initially responsive to anti-androgen therapy, however become resistant to this re...

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Autori principali: Putluri, Nagireddy, Shojaie, Ali, Vasu, Vihas T., Nalluri, Srilatha, Vareed, Shaiju K., Putluri, Vasanta, Vivekanandan-Giri, Anuradha, Byun, Jeman, Pennathur, Subramaniam, Sana, Theodore R., Fischer, Steven M., Palapattu, Ganesh S., Creighton, Chad J., Michailidis, George, Sreekumar, Arun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138744/
https://ncbi.nlm.nih.gov/pubmed/21789170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021417
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