Metabolomic Profiling Reveals a Role for Androgen in Activating Amino Acid Metabolism and Methylation in Prostate Cancer Cells

Prostate cancer is the second leading cause of cancer related death in American men. Development and progression of clinically localized prostate cancer is highly dependent on androgen signaling. Metastatic tumors are initially responsive to anti-androgen therapy, however become resistant to this re...

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Main Authors: Putluri, Nagireddy, Shojaie, Ali, Vasu, Vihas T., Nalluri, Srilatha, Vareed, Shaiju K., Putluri, Vasanta, Vivekanandan-Giri, Anuradha, Byun, Jeman, Pennathur, Subramaniam, Sana, Theodore R., Fischer, Steven M., Palapattu, Ganesh S., Creighton, Chad J., Michailidis, George, Sreekumar, Arun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138744/
https://ncbi.nlm.nih.gov/pubmed/21789170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021417
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