Exploiting Mitochondrial Dysfunction for Effective Elimination of Imatinib-Resistant Leukemic Cells

Challenges today concern chronic myeloid leukemia (CML) patients resistant to imatinib. There is growing evidence that imatinib-resistant leukemic cells present abnormal glucose metabolism but the impact on mitochondria has been neglected. Our work aimed to better understand and exploit the metaboli...

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Hauptverfasser: Kluza, Jérome, Jendoubi, Manel, Ballot, Caroline, Dammak, Abir, Jonneaux, Aurélie, Idziorek, Thierry, Joha, Sami, Dauphin, Véronique, Malet-Martino, Myriam, Balayssac, Stéphane, Maboudou, Patrice, Briand, Gilbert, Formstecher, Pierre, Quesnel, Bruno, Marchetti, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138741/
https://ncbi.nlm.nih.gov/pubmed/21789194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021924
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