Diminished metastasis in tetraspanin CD151–knockout mice

Tetraspanin protein CD151 on tumor cells supports invasion and metastasis. In the present study, we show that host animal CD151 also plays a critical role. CD151-null mice showed markedly diminished experimental lung metastasis after injection of Lewis lung carcinoma or B16F10 melanoma cells. Dimini...

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Hlavní autoři: Takeda, Yoshito, Li, Qinglin, Kazarov, Alexander R., Epardaud, Mathieu, Elpek, Kutlu, Turley, Shannon J., Hemler, Martin E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Vascular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138696/
https://ncbi.nlm.nih.gov/pubmed/21536858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-302240
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