Differential effects of HIV viral load and CD4 count on proliferation of naive and memory CD4 and CD8 T lymphocytes

We previously showed that HIV infection leads to expansion of a rapidly proliferating pool (s(1)) of CD4 and CD8 T lymphocytes. In the current study, we used in vivo labeling with bromodeoxyuridine to characterize the kinetics of naive, memory, and activated (HLA-DR(+)/CD38(+)) subpopulations of CD4...

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Autori principali: Srinivasula, Sharat, Lempicki, Richard A., Adelsberger, Joseph W., Huang, Chiung-Yu, Roark, Joshua, Lee, Philip I., Rupert, Adam, Stevens, Randy, Sereti, Irini, Lane, H. Clifford, Di Mascio, Michele, Kovacs, Joseph A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
Soggetti:
Clinical Trials and Observations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138680/
https://ncbi.nlm.nih.gov/pubmed/21562041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-335174
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