SLCO2B1 and SLCO1B3 May Determine Time to Progression for Patients Receiving Androgen Deprivation Therapy for Prostate Cancer

PURPOSE: Androgen deprivation therapy (ADT), an important treatment for advanced prostate cancer, is highly variable in its effectiveness. We hypothesized that genetic variants of androgen transporter genes, SLCO2B1 and SLCO1B3, may determine time to progression on ADT. PATIENTS AND METHODS: A cohor...

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Bibliografiske detaljer
Main Authors: Yang, Ming, Xie, Wanling, Mostaghel, Elahe, Nakabayashi, Mari, Werner, Lillian, Sun, Tong, Pomerantz, Mark, Freedman, Matthew, Ross, Robert, Regan, Meredith, Sharifi, Nima, Figg, William Douglas, Balk, Steven, Brown, Myles, Taplin, Mary-Ellen, Oh, William K., Lee, Gwo-Shu Mary, Kantoff, Philip W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2011
Fag:
Original Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138634/
https://ncbi.nlm.nih.gov/pubmed/21606417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.31.2405
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