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The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway

Post-transcriptional regulation of mRNA includes restriction mechanisms to prevent export and expression of mRNAs that are incompletely spliced. Here we present evidence that the mammalian protein Tpr is involved in this restriction. To study the role of Tpr in export of mRNA with retained introns,...

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Main Authors: Coyle, John H., Bor, Yeou-Cherng, Rekosh, David, Hammarskjold, Marie-Louise
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138570/
https://ncbi.nlm.nih.gov/pubmed/21613532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2616111
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