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The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway

Post-transcriptional regulation of mRNA includes restriction mechanisms to prevent export and expression of mRNAs that are incompletely spliced. Here we present evidence that the mammalian protein Tpr is involved in this restriction. To study the role of Tpr in export of mRNA with retained introns,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Coyle, John H., Bor, Yeou-Cherng, Rekosh, David, Hammarskjold, Marie-Louise
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138570/
https://ncbi.nlm.nih.gov/pubmed/21613532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2616111
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