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The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway

Post-transcriptional regulation of mRNA includes restriction mechanisms to prevent export and expression of mRNAs that are incompletely spliced. Here we present evidence that the mammalian protein Tpr is involved in this restriction. To study the role of Tpr in export of mRNA with retained introns,...

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Autors principals: Coyle, John H., Bor, Yeou-Cherng, Rekosh, David, Hammarskjold, Marie-Louise
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138570/
https://ncbi.nlm.nih.gov/pubmed/21613532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2616111
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