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HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit's decoding groove

Hepatitis C virus (HCV) uses a structured internal ribosome entry site (IRES) RNA to recruit the translation machinery to the viral RNA and begin protein synthesis without the ribosomal scanning process required for canonical translation initiation. Different IRES structural domains are used in this...

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Detalhes bibliográficos
Main Authors: Filbin, Megan E., Kieft, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138563/
https://ncbi.nlm.nih.gov/pubmed/21606179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2594011
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