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Differentiating analogous tRNA methyltransferases by fragments of the methyl donor

Bacterial TrmD and eukaryotic-archaeal Trm5 form a pair of analogous tRNA methyltransferase that catalyze methyl transfer from S-adenosyl methionine (AdoMet) to N(1) of G37, using catalytic motifs that share no sequence or structural homology. Here we show that natural and synthetic analogs of AdoMe...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lahoud, Georges, Goto-Ito, Sakurako, Yoshida, Ken-ichi, Ito, Takuhiro, Yokoyama, Shigeyuki, Hou, Ya-Ming
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138561/
https://ncbi.nlm.nih.gov/pubmed/21602303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2706011
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