Purification and antimicrobial properties of three defensins from rat neutrophils.

Three cysteine-rich cationic peptides, designated RatNP-1, RatNP-3, and RatNP-4, were purified from an acid extract of rat polymorphonuclear neutrophils, sequenced, and tested for antimicrobial activity. The peptides ranged from 29 to 32 amino acids in length (Mr, 3,252 to 3,825), and each contained...

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Pubblicato in:	Infect Immun
Autori principali:	Eisenhauer, P B, Harwig, S S, Szklarek, D, Ganz, T, Selsted, M E, Lehrer, R I
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313836/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.7.2021-2027.1989
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