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Purification and antimicrobial properties of three defensins from rat neutrophils.

Three cysteine-rich cationic peptides, designated RatNP-1, RatNP-3, and RatNP-4, were purified from an acid extract of rat polymorphonuclear neutrophils, sequenced, and tested for antimicrobial activity. The peptides ranged from 29 to 32 amino acids in length (Mr, 3,252 to 3,825), and each contained...

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Detalles Bibliográficos
Publicado en:Infect Immun
Principais autores: Eisenhauer, P B, Harwig, S S, Szklarek, D, Ganz, T, Selsted, M E, Lehrer, R I
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313836/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543629/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.7.2021-2027.1989
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