Wnt/β-Catenin Pathway in Podocytes Integrates Cell Adhesion, Differentiation, and Survival

Diabetic kidney disease (DKD) is the single most common cause of albuminuria and end-stage kidney disease in the United States. We found increased expression of Wnt/β-catenin (Ctnnb1) pathway transcripts and proteins in glomeruli and podocytes of patients and mouse models of DKD. Mice with podocyte-...

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Главные авторы: Kato, Hideki, Gruenwald, Antje, Suh, Jung Hee, Miner, Jeffrey H., Barisoni-Thomas, Laura, Taketo, Makoto M., Faul, Christian, Millar, Sarah E., Holzman, Lawrence B., Susztak, Katalin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2011
Предметы:
Molecular Bases of Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138306/
https://ncbi.nlm.nih.gov/pubmed/21613219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.223164
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