Differential but Competitive Binding of Nogo Protein and Class I Major Histocompatibility Complex (MHCI) to the PIR-B Ectodomain Provides an Inhibition of Cells

Binding of class I MHC molecules (MHCI) to an inhibitory receptor, PIR-B, expressed on B cells and myeloid cells provides constitutive cellular inhibition, thus ensuring peripheral tolerance. Recent unexpected findings pointed to a novel inhibitory role of PIR-B in neurite regeneration through bindi...

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Main Authors: Matsushita, Haruka, Endo, Shota, Kobayashi, Eiji, Sakamoto, Yuzuru, Kobayashi, Keisuke, Kitaguchi, Kohji, Kuroki, Kimiko, Söderhäll, Arvid, Maenaka, Katsumi, Nakamura, Akira, Strittmatter, Stephen M., Takai, Toshiyuki
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138294/
https://ncbi.nlm.nih.gov/pubmed/21636572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.157859
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