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Regulation of cytotoxic T lymphocyte triggering by PIR-B on dendritic cells

Priming of cytotoxic T lymphocytes (CTLs) by dendritic cells (DCs) is crucial for elimination of pathogens and malignant cells. To activate CTLs, DCs present antigenic peptide-complexed MHC class I molecules (MHC-I) that will be recognized by the CTLs with T cell receptors and CD8 molecules. Here we...

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Autors principals: Endo, Shota, Sakamoto, Yuzuru, Kobayashi, Eiji, Nakamura, Akira, Takai, Toshiyuki
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533681/
https://ncbi.nlm.nih.gov/pubmed/18787130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804571105
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