Increasing Hydrophobicity or Disulfide Bridging at the Factor VIII A1 and C2 Domain Interface Enhances Procofactor Stability

Lignende værker

• Replacing the Factor VIII C1 Domain with a Second C2 Domain Reduces Factor VIII Stability and Affinity for Factor IXa
  af: Wakabayashi, Hironao, et al.
  Udgivet: (2013)
• Factor VIII Lacking the C2 Domain Retains Cofactor Activity in Vitro
  af: Wakabayashi, Hironao, et al.
  Udgivet: (2010)
• Identification of Residues Contributing to A2 Domain-dependent Structural Stability in Factor VIII and Factor VIIIa
  af: Wakabayashi, Hironao, et al.
  Udgivet: (2008)
• Combining mutations of charged residues at the A2 domain interface enhances factor VIII stability over single point mutations
  af: Wakabayashi, Hironao, et al.
  Udgivet: (2008)
• Modification of inter-domain interfaces within the A3C1C2 subunit of factor VIII affects its stability and activity
  af: Wakabayashi, Hironao, et al.
  Udgivet: (2013)